validated stability indicating hplc method for the determination of mebeverine in the presence of its degradation products: kinetics study of its degradation in oxidative condition
Authors
abstract
similar resources
a stability indicating hplc method for determination of mebeverine in the presence of its degradation products and kinetic study of its degradation in oxidative condition
an hplc method for determination of mebeverine hydrochloride (mh) in the presence of its degradation products was developed. the degradation of mh was studied under hydrolysis, oxidative and photolysis stress conditions. under alkaline, acidic and oxidative conditions, degradation of mh was observed. the separation was performed using a symmetry c 18 column and a mixture of 50 mm kh 2 po 4 , ac...
full textA stability indicating HPLC method for determination of mebeverine in the presence of its degradation products and kinetic study of its degradation in oxidative condition
An HPLC method for determination of mebeverine hydrochloride (MH) in the presence of its degradation products was developed. The degradation of MH was studied under hydrolysis, oxidative and photolysis stress conditions. Under alkaline, acidic and oxidative conditions, degradation of MH was observed. The separation was performed using a Symmetry C18 column and a mixture of 50 mM KH2PO4, acetoni...
full textValidated stability-indicating HPLC method for the determination of mesna in presence of its degradation products.
A rapid and simple stability-indicating liquid chromatographic method was developed and validated for analysis of mesna in the presence of its degradation products in drug substance and drug products in a run time not >5 min. The separation was achieved on a RP amide C16 column at room temperature using methanol-phosphate buffer (10:90, v/v, pH 3.0) as mobile phase at a flow rate of 1 mL min(-1...
full textstudy of cohesive devices in the textbook of english for the students of apsychology by rastegarpour
this study investigates the cohesive devices used in the textbook of english for the students of psychology. the research questions and hypotheses in the present study are based on what frequency and distribution of grammatical and lexical cohesive devices are. then, to answer the questions all grammatical and lexical cohesive devices in reading comprehension passages from 6 units of 21units th...
Validated stability indicating methods for determination of nitazoxanide in presence of its degradation products*
Three sensitive, selective and reproducible stability-indicating methods are presented for determination of nitazoxanide (NTZ), a new anti-protozoal drug, in presence of its degradation products. Method A utilizes the first derivative of ratio spectra spectrophotometry by measurement of the amplitude at 364.4 nm using one of the degradation products as a divisor. Method B is a chemometric-assis...
full textMy Resources
Save resource for easier access later
Journal title:
research in pharmaceutical sciencesجلد ۷، شماره ۵، صفحات ۰-۰
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023